Admittance To Determine Left Ventricular Pressure - Volume Relations In Mice

Introduction and Background

The admittance system, currently utilized for animal research, has future application for physicians in direct patient care settings. While currently a research model, the ultimate goal is to scale the device for use in patients during heart catheterization for individuals with congestive heart failure. We want to determine how new drugs and devices will be of assistance to the failing human heart.

Why Take Our Course

These applications will utilize all the identical concepts currently being taught in our admittance course, which ultimately will impact directly on patient care. The admittance course is uniquely poised to move medicine from bench to bedside since the course, as currently designed, will assess physician and research scientist competence and performance related to the use of the admittance system. The ultimate goal is for physician researchers and scientists to maximize the quality of data obtained from animal studies, and physicians to implement what they learn in this course to treat patients with congestive heart failure.

Target Audience

Physicians, PhDs, Laboratory Assistants and Advanced Degrees

Course Objectives

Upon successful completion of this course participants will be able to:

• Discuss the theory behind the use of admittance, and its advantages over the old fashion conductance technique.
• Perform saline calibration of the admittance system to assure accurate operation.
• Perform the murine cardiac surgery required to use the admittance system in rodents.

• Discuss the new technique of measurement of epicardial left ventricular conductivity and permittivity in mice.
• Enter this data into the software of the admittance system for accurate use of the equipment.
• Convert admittance into true left ventricular volume.
• Interpret and analyze left ventricular pressure-volume relations, particularly during transient occlusion of the inferior vena cava.
• Discuss how the admittance system can best be utilized to answer your research objectives, and maximize the quality of your data for peer review.
• Effectively translate this research application into clinical practice setting.
• Discuss potential benefit to physicians who treat patients with congestive heart failure.

Registration Fees

Continuing Education Credit

CME: The UT Health Science Center San Antonio School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The UT Health Science Center San Antonio School of Medicine designates this educational activity for a maximum of 6.75 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

MPCEC: This educational activity has been approved by CAMPEP for 6.75 MPCEC.